TY  - GEN
T1  - Caenorhabditis elegans che-5 is allelic to gcy-22
AU  - Kunitomo, Hirofumi
AU  - Iino, Yuichi
DO  - 10.17912/micropub.biology.000313
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000313/
AB  - Mechanisms of chemotactic behaviors have been of great interest in C. elegans neuroscience since the early days of its research (Ward 1973). Lewis and Hodgkin (1977) systematically isolated more than ten abnormal chemotaxis (che) mutants that showed defective chemotaxis to sodium (Na+) and chloride (Cl–) ions (Lewis and Hodgkin 1977), whose responsible genes have already been molecularly characterized except for che-5(e1073). We here show that che-5(e1073) is a missense allele of gcy-22, which encodes a receptor guanylyl cyclase (rGC) specifically expressed in the ASE-right (ASER) gustatory neuron and is essential for chemosensation through the neuron.
PY  - 2020
JO  - microPublication Biology
ER  -