TY - GEN T1 - Variation between nematodes in a multi-sensory behavioral assay AU - Ellis, Renae AU - Harris, Gareth DO - 10.17912/micropub.biology.000330 UR - http://beta.micropublication.org/journals/biology/micropub-biology-000330/ AB - An environment is often represented by numerous sensory cues. In order to better survive, an animal often needs to detect and process sensory cues simultaneously to make an appropriate behavioral decision. The Caenorhabditis elegans (C. elegans) genome encodes homologues of a significant number of molecules expressed in mammalian brains, which allows characterizing of the molecular and circuit basis for multi-sensory behavior during decision-making (Bargmann, 1998). In addition, studies have demonstrated various genes and neurons in behavioral differences previously observed in sensory behavior and decision-making when comparing different organisms, such as, nematodes. These variations in behavior involve differences in neuronal signals and neurons. For example, catecholamine signaling, neuropeptide Y-like receptors and pheromone chemoreceptors (Debono and Bargmann, 1998, Srinivasan et al.., 2008; Bendesky et al.., 2010, Mcgraph et al.., 2011). In this study, we investigate the behavioral differences across various species of nematodes, by examining multiple types of Caenorhabditis species and how they may differ in a multi-sensory behavioral assay (Harris et al.., 2019). The multisensory behavioral assay involves examining how different species of nematodes that are exposed to conflicting cues, behave when compared to the standard wild type, C. elegans Bristol N2 worms. We use a multi-sensory behavior paradigm to address these questions to determine any difference in ‘2-nonanone-dependent food leaving’, that assesses food leaving during exposure to the repellent 2-nonanone. Wild type N2 C. elegans were examined as the control in comparison to other Caenorhabditis species, including, Caenorhabditis remanei (C. remanei), Caenorhabditis nouraguensis (C. nouraguensis), and Caenorhabditis portoensis (C. portoensis). PY - 2020 JO - microPublication Biology ER -