TY  - GEN
T1  - Mutating two putative phosphorylation sites on ZHP-3 does not affect its localization or function during meiotic chromosome segregation
AU  - Russo, Anna E.
AU  - Nelson, Christian R.
AU  - Bhalla, Needhi
DO  - 10.17912/micropub.biology.000354
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000354/
AB  - Haploid sex cells such as sperm and eggs depend on a specialized form of cell division called meiosis. Throughout prophase of meiosis, homologous chromosomes pair, synapse, and recombine to form a physical link between them called a chiasma. Chiasmata are essential for proper segregation (Page et al. 2003). Defects in meiotic recombination can lead to gametes that contain an incorrect number of chromosomes (aneuploidy), which can cause infertility, miscarriages, and genetic disorders such as Down Syndrome. Therefore, identifying how recombination is regulated is crucial for understanding multiple aspects of human reproductive health.
PY  - 2021
JO  - microPublication Biology
ER  -