TY - GEN T1 - YML018C protein localizes to the vacuolar membrane independently of Atg27p AU - Sturgeon, Candyce M. AU - Zanghi, Nicholas AU - Smith, Hannah M. AU - Davis, Emily K. AU - Robinson, Meaghan R. AU - Cabrera, Elizabeth AU - Holbrook, Molly C. AU - Segarra, VerĂ³nica A. DO - 10.17912/micropub.biology.000391 UR - http://beta.micropublication.org/journals/biology/micropub-biology-000391/ AB - Large-scale studies have localized the uncharacterized YML018C protein to the vacuolar membrane and have identified the autophagy-related protein Atg27p as one of its 10 physical interactors (Huh et al., 2003; Tarasov et al., 2008). These two findings suggested a potential role for the YML018C protein in the process of autophagy. In silico methods predict that the YML018C protein has 8 transmembrane domains, with both N- and C-terminal regions facing the cytoplasm (Krogh et al., 2000). Structure prediction algorithms identify the YML018C protein as a candidate GDP-mannose (or nucleotide sugar) transporter (Kelley et al., 2015). PY - 2021 JO - microPublication Biology ER -