TY  - GEN
T1  - Ecdysone and 20-hydroxyecdysone are not required to activate glycolytic gene expression in Drosophila melanogaster embryos
AU  - Tennessen, Jason M.
DO  - 10.17912/micropub.biology.000501
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000501/
AB  - During the course of the Drosophila development, metabolism readily adapts to meet the energetic and biosynthetic demands of each life stage (Gillette et al., 2021). This relationship between growth and metabolism is particularly apparent when examining changes in glycolytic gene expression. Approximately midway through embryonic development, transcripts representing nearly every enzyme involved in glycolysis are coordinately up-regulated (Abu-Shumays and Fristrom, 1997; Currie and Sullivan, 1994a, b; Madhavan et al., 1972; Roselli-Rehfuss et al., 1992; Shaw-Lee et al., 1992; Shaw-Lee et al., 1991; Sun et al., 1988; Tennessen et al., 2011; Tennessen et al., 2014; Tixier et al., 2013; Wright and Shaw, 1970). The resulting glycolytic program is maintained throughout the larval growth period and subsequently down-regulated prior to the onset of metamorphosis (White et al., 1999). These metabolic transitions are highly predictable and provide an opportunity to understand how metabolism adapts to meet the energetic demands of insect development.
PY  - 2021
JO  - microPublication Biology
ER  -