TY  - GEN
T1  - moc-6/MOCS2A is necessary for molybdenum cofactor synthesis in C. elegans
AU  - Snoozy, Jennifer
AU  - Breen, Peter C
AU  - Ruvkun, Gary
AU  - Warnhoff, Kurt
DO  - 10.17912/micropub.biology.000531
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000531/
AB  - The nematode C. elegans has recently emerged as a tractable system for genetic discovery in Moco biology (Warnhoff and Ruvkun 2019; Warnhoff et al. 2021). In C. elegans, endogenous Moco biosynthesis is not required for growth, development, and reproduction. C. elegans mutants defective in Moco biosynthesis are viable because they acquire and use Moco from their bacterial diet (Warnhoff and Ruvkun 2019; Warnhoff et al. 2021). Thus, C. elegans has 2 redundant pathways for maintaining cellular Moco: endogenous synthesis and dietary acquisition. C. elegans is the only known animal for which Moco biosynthesis is dispensable.
PY  - 2022
JO  - microPublication Biology
ER  -