TY  - GEN
T1  - The Effect of an Environmentally Relevant Phthalate Mixture on Primordial Germ Cells of Xenopus laevis Embryos
AU  - Momplaisir, Nathalie Lancy
AU  - Turgeon, Aurora
AU  - Flaws, Jodi
AU  - Yang, Jing
DO  - 10.17912/micropub.biology.000080
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000080/
AB  - Phthalates, being considered endocrine disrupting chemicals, are estrogen-like and anti-androgenic compounds that interfere with hormones which regulate numerous biological processes, including the maintenance of homeostasis and the regulation of development (Kavlock et al., 1996). Toxicological studies have consistently shown that phthalate metabolites are reproductive and developmental toxicants (Jeng, 2014). Some of the significant complications include fertility issues, decreased anogenital distance, low sperm concentration and motility. While the adverse effects of phthalates on the reproductive system have been well-documented, it is currently unclear if exposure to phthalates affects early stage of germline development.
PY  - 2018
JO  - microPublication Biology
ER  -