TY  - GEN
T1  - The autophagy gene product BEC-1 supports normal aging and neurodevelopment in Caenorhabditis elegans: Integration
AU  - Ashley, Nicholas
AU  - Holgado, Andrea M
DO  - 10.17912/micropub.biology.000102
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000102/
AB  - Aging can be defined by many different physiological pathways that emphasize changes in a variety of cells and tissues. Disease and death are often results of aging (Viña et al., 2013). However, specific mechanisms in different cell types offer multiple hypotheses regarding the definition of aging (Viña et al., 2007). Although some researchers target specific aspects of physiological processes as major contributors to aging, such as free radical theory (Harman, 2003), inflammation theory (Chung et al., 2001), mitochondrial theory (Cadenas and Davies, 2000; Sastre et al., 2000), immunologic theory (Franceschi et al., 2000), current hypotheses suggest that aging results from alterations of multiple systems working at the same time (Weinert and Timiras, 2003). Central Nervous System neural networks have been identified as particularly important for understanding cellular processes that cause aging, which is partly characterized by cell death (Yonekawa and Thorburn, 2013).
PY  - 2019
JO  - microPublication Biology
ER  -