TY  - GEN
T1  - C. elegans srf-6 and nsy-1 mutations result in a similar 2AWCON phenotype and do not complement (srf-6 is nsy-1 II)
AU  - Honzel, Brooke E
AU  - Foley, Stephen J
AU  - Politz, Samuel M
DO  - 10.17912/micropub.biology.000128
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000128/
AB  - C. elegans srf-6 mutants were isolated using altered surface immunofluorescence as phenotype (Hemmer et al., 1991; Grenache et al., 1996). In Van Sciver et al., 2019, we showed by whole genome sequencing that three different srf-6 mutants carry mutations in gene nsy-1. Well-characterized mutant alleles of nsy-1 result in hermaphrodites that express the olfactory receptor gene str-2 in both AWC neurons (2AWCON, Troemel et al., 1999), unlike wild type hermaphrodites, which express str-2 asymmetrically in only one of the two AWC neurons (1AWCON, Troemel et al., 1999). Our sequencing results suggested that srf-6 mutants might have a similar 2AWCONphenotype.  We therefore examined srf-6(yj13) for its AWC phenotype.
PY  - 2019
JO  - microPublication Biology
ER  -