TY  - GEN
T1  - Genome editing of Caenorhabditis briggsae using CRISPR/Cas9 co-conversion marker dpy-10
AU  - Cohen, Sarah M
AU  - Sternberg, Paul W
DO  - 10.17912/micropub.biology.000171
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000171/
AB  - Genomic editing of the roundworm Caenorhabditis elegans using the CRISPR/Cas9 system has allowed for widespread creation of null mutants – vital for scientific understanding of this model organism. A closely-related nematode species, Caenorhabditis briggsae, is emerging as an alternative model organism to better understand how findings in C. elegans can broaden and develop the larger field of nematology (Gupta et al. 2007). To that end, we have developed an effective and efficient co-conversion CRISPR/Cas9 system for use in C. briggsae using the gene dpy-10.
PY  - 2019
JO  - microPublication Biology
ER  -