TY  - GEN
T1  - Caenorhabditis elegans daf-7 mutants exhibit burrowing behavior
AU  - López-Puebla, Araceli
AU  - Mayoral-Peña, Zyanya
AU  - Gómez-Cepeda, Kitzia
AU  - Arellano-Carbajal, Fausto
DO  - 10.17912/micropub.biology.000172
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000172/
AB  - Burrowing was originally described for C. elegans as worms that tended to stay below the surface of the agar when maintaining high densities of nematodes on agar (Hodgkin and Doniach, 1997). The neuropeptide receptor NPR-1 regulates food-related behaviors (de Bono and Bargmann, 1998). The canonical TGF-β signaling pathway responds to environmental signals by regulating egg laying and feeding (Gumienny and Savage-Dunn, 2013). The TGF-β like ligand DAF-7 functions as a sensor of environmental conditions (Greer et al., 2008). As the aggregating mutant strain npr-1 appeared to burrow more than the wild-type N2 strain (Hodgkin and Doniach, 1997; de Bono and Bargmann, 1998), it was suggested that aggregation preludes burrowing (Rogers et al., 2006). Considering that daf-7 mutants also aggregate on food (Thomas et al., 1993; de Bono et al., 2002), we examined whether daf-7 mutants also exhibit burrowing behavior.
PY  - 2019
JO  - microPublication Biology
ER  -