TY  - GEN
T1  - Disruption of the histone acetyltransferase GCN5 and the transcriptional coactivator ADA2b affect trichome density in Arabidopsis thaliana
AU  - Kotak, Jenna
AU  - Kendig, Ashley
AU  - Cann, Kelly
AU  - Shaffer, Joshua
AU  - Hark, Amy T
AU  - McCain, Elizabeth R
DO  - 10.17912/micropub.biology.000174
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000174/
AB  - GCN5 is a histone acetyltransferase that is well-conserved in eukaryotic species and has been shown to play roles in global histone modification and gene expression.  The transcriptional coactivator ADA2 works with GCN5 and other regulators in these processes (Candau et al. 1997; Grant et al. 1997); in Arabidopsis thaliana the functional paralog is referred to as ADA2b (Hark et al. 2009).  Pleiotropic phenotypes of plants with T-DNA insertions at these loci were first reported fifteen years ago (Vlachonasios et al. 2003; Bertrand et al. 2003).  Since then, we and others have sought to understand the roles of GCN5 and ADA2b in specific developmental pathways.  We recently reported that rosette leaf trichomes display altered ploidy and branching morphology in gcn5 and ada2b mutants (Kotak et al. 2018). This suggests that these chromatin factors impact later steps in trichome morphogenesis (Hulskamp 2004).
PY  - 2019
JO  - microPublication Biology
ER  -