TY  - GEN
T1  - Arabidopsis Heat Shock Granules exhibit dynamic cellular behavior and can form in response to protein misfolding in the absence of elevated temperatures
AU  - Lawrence, Rosalie
AU  - Kaplinsky, Nick
DO  - 10.17912/micropub.biology.000285
UR  - http://beta.micropublication.org/journals/biology/micropub-biology-000285/
AB  - In response to a heat shock (HS), plants, like all eukaryotic organisms, exhibit a highly conserved and coordinated cellular program called the heat shock response (HSR). The HSR includes the expression of genes involved in protecting cells from the deleterious effects of high temperatures. In addition, HS leads to the formation of non-membrane-bound assemblies of proteins and RNAs that play important roles in responding to cellular stress (Wallace et al., 2015). Molecular chaperones known as heat shock proteins (HSPs) are expressed during a HSR. Small HSPs (sHSPs) produced during the HSR bind to misfolded proteins and prevent their irreversible aggregation while other families of HSPs facilitate the refolding of misfolded proteins in an ATP dependent manner (Richter et al., 2010; Haslbeck and Vierling, 2015).
PY  - 2020
JO  - microPublication Biology
ER  -